The Journal of Organic Chemistry

Angewandte Chemie International Edition

Heng Jiang, Armido Studer

The visible-light-promoted decarboxylation of α-imino-oxy propionic acids for the generation of iminyl radicals has been accomplished through the use of Ir(dFCF3ppy)2(dtbbpy)PF6 as a photoredox catalyst. Different from visible-light promoted homolysis and single-electron-reduction of oxime derivatives, this strategy provides a novel catalytic cycle for alkene carboimination through a sequence comprising N-radical generation, iminyl radical cyclization, intermolecular conjugate addition to a Michael acceptor, and single electron reduction to afford various pyrroline derivatives in an overall redox-neutral process. The indolizidine alkaloid skeleton could be easily constructed from a pyrroline derivative prepared by this synthetic method.

Dhevalapally Ramachary, Anif Pasha Mohammed, Thirupathi Guguloth

Pharmaceutically and structurally important methanobenzo[7]annulenes were synthesized in very good yields with excellent enantio- and diastereoselectivities through an unprecedented competitive organocatalytic formal [3+2]-cycloaddition from the readily available 2-alkyl-3-hydroxynaphthalene-1,4-diones and alkyl vinyl ketones.

Organic Letters

Yun Li, Qingyu Zhang, Hongyu Wang, Bin Cheng and Hongbin Zhai

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Organic LettersDOI: 10.1021/acs.orglett.7b02124
Xiaoyang Wang, Shuang Zhao, Jing Liu, Dingsheng Zhu, Minjie Guo, Xiangyang Tang and Guangwei Wang

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Organic LettersDOI: 10.1021/acs.orglett.7b01712
Guanglong Sun, Xue Lv, Yinan Zhang, Min Lei and Lihong Hu

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Organic LettersDOI: 10.1021/acs.orglett.7b01882
Xiaodong Xiong, Fei Tan and Ying-Yeung Yeung

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Organic LettersDOI: 10.1021/acs.orglett.7b01899
Adisak Chatupheeraphat, Hsuan-Hung Liao, Shao-Chi Lee and Magnus Rueping

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Organic LettersDOI: 10.1021/acs.orglett.7b01905
Guangzheng Wei, Chunmei Chen, Qingyi Tong, Jinfeng Huang, Wenjing Wang, Zhaodi Wu, Jing Yang, Junjun Liu, Yongbo Xue, Zengwei Luo, Jianping Wang, Hucheng Zhu and Yonghui Zhang

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Organic LettersDOI: 10.1021/acs.orglett.7b02146

Nano Letters

Daesu Lee, Jaeseong Lee, Kyung Song, Fei Xue, Si-Young Choi, Yanjun Ma, Jacob Podkaminer, Dong Liu, Shih-Chia Liu, Bongwook Chung, Wenjuan Fan, Sang June Cho, Weidong Zhou, Jaichan Lee, Long-Qing Chen, Sang Ho Oh, Zhenqiang Ma and Chang-Beom Eom

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Nano LettersDOI: 10.1021/acs.nanolett.7b02482


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